P-21: Morphological Changes of Fallophian Tube after Application of Estrogen and Progesterone during Luteal Phase in the Superovulated Mice

Background: The fallopian tube serves as optimal environment for the transport of gamets, fertilization and early development of embryo. In this study, the morphological assessment of superovulated mice fallopian tube were investigated at window implantation period. Materials and Methods: Female mice were superovualated then were mated with vasectomized mice; the mice were divided in experimental and control groups. Experimental group included five groups: 1-progesterone (P), 2-estrogen (E), 3-estrogen + progesterone, 4-antiprogesterone + estrogen and 5-sham group. The fallopian tubes of all groups were collected after 4.5 day of pseudopregnancy and were prepared for histological l studies. Results: Morphological studies of fallopian tube showed that administration of progesterone increased the number of peg cells in the epithelium of fallopian tube while esterogen injection increased the number of cillitaed cells in comparison to controle groups .also estrojen increased the high of cillitaed cells and combination of E and P increased the high of cillitaed cells . Conclusion: It is concluded that the adding of E to P may improve fallopian tube condition to fertilization at luteal phase.